Dean's World

Defending the liberal tradition in history, science, and philosophy.

Thalidomide: A Positive Use

I've always been fascinated by the drug thalidomide, which proponents of strict controls on drug companies often use as their favorite example of why we absolutely need the strictest possible rules about drugs being released to the general public. I find it fascinating on multiple levels, not least being that it's been over a half-century since that drug was banned and it's still everyone's favorite example.

While I take no strong position one way or the other, I find it fascinating that we're discovering possible positive uses for dangerous drugs. And, in looking at that, I think: shouldn't this serve as a reminder that practically any drug may be useful and practically any drug is dangerous?

Posted by Dean | Permalink | Technorati Trackbacks
Scott McLoud (mail):
Dean,

I don't normally agree with you when you delve into scientific stuff, but here is an obvious case of hysteria overwhelming reason in application of science. I had to clear the cobwebs to remember OChem from a decade ago and a class session we had on this. This drug could be pretty effectively controlled by our current scheme of prescription meds where a big red sign says to the doctor "Do not prescribe to women of child-bearing age, regardless of whether they are pregnant or not". Then it could be freed up for use for a lot of conditions or diseases where it is desperately needed.
2.29.2008 3:09pm
Dean Esmay:
You don't "normally" agree with me? What do you normally disagree with?
2.29.2008 3:22pm
Dean Esmay:
And by the way, the linked article clearly states that it's being used to treat ovarian cancer, which of course afflicts women of child-bearing age.
2.29.2008 3:23pm
B. Durbin (www):
I thought I'd heard that they had pinpointed the problem with thalidomide births, namely that thalidomide depleted the body of certain essential nutrients (vitamin A being one of them) and that an added supplement actually made the drug safe again.

I could be wrong, since it's been literally years since I read about this, but it's interesting if true.
2.29.2008 3:45pm
Scott McLoud (mail):
Well, I disagree with you on the HIV-AIDS link posts you put up. They're interesting and make some good points but on balance I disagree based on my (short) background in infectious disease research.
2.29.2008 4:14pm
Dean Esmay:
Ah.
2.29.2008 4:22pm
maggie may - labrat:
shouldn't this serve as a reminder that practically any drug may be useful and practically any drug is dangerous?

Yep - I personally knew 3 people who died from normally therapeutic doses of tylenol. Millions take it safely every day - but I just can't take the stuff. No acetaminophen in my house.

Irrational? Of course.
2.29.2008 6:52pm
Jeff Licquia (mail) (www):
Drugs are dangerous. The question is: are they less dangerous than no drugs?
2.29.2008 7:03pm
maor (mail):
I think they simply avoid giving thalidomide to pregnant women, which pretty much solves the problem. It wouldn't be necessary to avoid all women who could potentially become pregnant.
3.1.2008 5:26pm
Account:
Password:
Remember info?
Commenting on Dean's World is a privilege, not a right. Dean is your host, you are his guest, and you should behave in that fashion. Dean is not your babysitter, nor is he your punching bag. Please remember this. In general, you are free to disagree with anyone on any subject you wish, but abusive behavior will not be tolerated.

Of course we all lose our tempers now and then. Dean freely admits to being imperfect in this regard, which is why regulars to this establishment will generally be cut more slack than people who we don't know very well.

Still: behave like an adult, or go find somewhere else to play. Thanks.